Pair Name	Cordycepin, Anti-CTLA-4 antibody
Disease Info	[ICD-11: 2B90]	Colon cancer		Investigative
Biological Phenomena	Induction-->Immunomodulatory
In Vitro Model	MC-38	Mouse colon adenocarcinoma	Mus musculus (Mouse)	CVCL_B288
	CT26	Mouse colon adenocarcinoma	Mus musculus (Mouse)	CVCL_7254
In Vivo Model	1×10⁶ MC38 cells in 100 µL of PBS and injected them subcutaneously (s.c.) into the right flank of C57BL/6J mice. In a similar manner, we injected 1×10⁶ CT26 cells, also suspended in 100 µL of PBS, s.c. into the right flank of Balb/c mice.
Result	Our current study successfully established a combination therapeutic strategy utilizing cordycepin and CTLA-4 blockade. This strategy demonstrated a significant synergistic effect against cancer, highlighting its importance in cancer treatment.